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| Ezetimibe Basic information |
| Description Indications and Usage Mechanisms of Action References |
| Product Name: | Ezetimibe |
| Synonyms: | (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one;Ezetimibe-001;Ticagrelor and its interMediate;Ezetimibe 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;Ezatimibe;zetia/vytorin;SCH 60969;Ezetimibe, >=99% |
| CAS: | 163222-33-1 |
| MF: | C24H21F2NO3 |
| MW: | 409.43 |
| EINECS: | 682-606-0 |
| Product Categories: | Isotope;CEDAX;Final material;API;Cardiovascular APIs;Ezetimibe;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;163222-33-1 |
| Mol File: | 163222-33-1.mol |
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| Ezetimibe Chemical Properties |
| Melting point | 164-166°C |
| alpha | D22 -33.9° (c = 3 in methanol) |
| Boiling point | 654.9±55.0 °C(Predicted) |
| density | 1.334±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml) |
| pka | 9.72±0.30(Predicted) |
| form | powder |
| color | White or off-white |
| BCS Class | 2 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChI | InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1 |
| InChIKey | OLNTVTPDXPETLC-XPWALMASSA-N |
| SMILES | N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O |
| CAS DataBase Reference | 163222-33-1(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)- (163222-33-1) |
| Safety Information |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25 |
| HS Code | 29337900 |
| Hazardous Substances Data | 163222-33-1(Hazardous Substances Data |
